Journal: Scientific Reports

Article Title: Facile tuning of the mechanical properties of a biocompatible soft material

doi: 10.1038/s41598-019-43579-8

Figure Lengend Snippet: On-chip temperature evaluation. ( a ) Cross section considered for temperature measurements and location of the relative positions of the thermocouples used to calibrate the temperature in real time. ( b ) Geometry used for the 2D numerical simulations. ( c ) Distribution of temperature at steady state, as obtained for the case T hot = 45 °C and T cold = 40 °C. ( d ) Temperature gradients across the channel length. In the schematic, the red horizontal arrow indicates the direction along which the temperature gradient is evaluated. The two graphs report the gradient of temperature inside the channel in the device with the PDMS membrane (left) and in the dummy device (right). In both cases the gradient is linear, with difference between the two situations being negligible.

Article Snippet: Additionally, we performed 2D numerical simulations (COMSOL Multiphysics 4.4a, Massachusetts, USA) to evaluate the cross-sectional distribution of temperature in the middle plane of the device (Fig. ).

Techniques: Membrane

Journal: bioRxiv

Article Title: Electroadhesive hydrogel interface for prolonged mucosal theranostics

doi: 10.1101/2023.12.19.572448

Figure Lengend Snippet: A ) e-GLUE’s adhesion strength on gastric mucosal tissue in vivo under various electrical stimulation conditions. B ) Maximum temperature of local gastric tissue under various electrical stimulation conditions. The temperature was measured using an IR camera during terminal experiments where the pig was under anesthesia. C ) IR images illustrating temperature distribution on the mucosal tissue before (0 s) and after (80 s) electrical stimulation treatment at a voltage amplitude of 10 V. D ) Maximum temperature of local mucosal tissue over 80 s. E ) Representative histological images of gastric mucosal tissues before and after electrical stimulation (E+) under optimal conditions (10 V, 80 s). Dashed rectangles indicate the regions around the e-GLUE’s perimeter. F ) 3D electromagnetic-bioheat transfer simulations using COMSOL Multiphysics (version 6.0) to visualize spatial-temporal temperature distribution in the hydrogel-tissue coupling structure in the depth direction over 80 s. The voltage amplitude in Fig. C, D , and F was set at 10 V. Values in panels A, B , and D represent the mean and the standard deviation (n = 3-4).

Article Snippet: We developed a numerical electromagnetic simulation using COMSOL Multiphysics (version 6.0, Extended text) to visualize the electrical field distribution with different electrode shapes ( , fig. S9 ).

Techniques: In Vivo, Standard Deviation